Scores:
- San Diego Padres 12 – Cincinnati Reds 5
- New York Yankees 4 – St. Louis Cardinals 11 (Game 1 of DH)
- Boston Red Sox 7 – Toronto Blue Jays 6
- Houston Astros 2 – Texas Rangers 5
- Minnesota Twins 1 – Baltimore Orioles 0
- Washington Nationals 4 – Philadelphia Phillies 19
- Milwaukee Brewers 11 – Pittsburgh Pirates 8
- Chicago White Sox 6 – Oakland Athletics 7 (10 innings) (See Chicago Sports Recap)
- Miami Marlins 0 – Atlanta Braves 7
- San Francisco Giants 1 – New York Mets 4
- Cleveland Guardians 6 – Chicago Cubs 0 (See Chicago Sports Recap)
- Los Angeles Dodgers 4 – Kansas City Chiefs 6
- Tampa Bay Rays 3 – Seattle Mariner 8
- New York Yankees 6 – St. Louis Cardinals 2 (Game 2 of DH)
- Detroit Tigers 4 – Colorado Rockies 2 (10 innings)
- Arizona Diamondbacks 3 – Los Angeles Angels 1