Scores:
- Boston Red Sox 8 – New York Yankees 1
- Kansas City Royals 4 – Chicago Cubs 6 (See Chicago Sports Recap)
- Miami Marlins 1 – Los Angeles Dodgers 3 (Game 1 of DH)
- Milwaukee Brewers 6 – Texas Rangers 1
- Philadelphia Phillies 12 – Washington Nationals 3
- Toronto Blue Jays 4 – Cincinnati Reds 3
- Detroit Tigers 4 – Cleveland Guardians 2
- Pittsburgh Pirates 7 – Minnesota Twins 4
- Seattle Mariners 10 – Houston Astros 3
- New York Mets 13 – St. Louis Cardinals 2
- San Francisco Giants 5 – Atlanta Braves 6
- Chicago White Sox 5 – Colorado Rockies 11 (See Chicago Sports Recap)
- Arizona Diamondbacks 8 – San Diego Padres 1
- Baltimore Orioles 7 – Oakland Athletics 2 (10 innings)
- Tampa Bay Rays 18 – Los Angeles Angels 4
- Miami Marlins 1 – Los Angeles Dodgers 3 (Game 2 of DH)