Scores:
- St. Louis Cardinals 6 – Pittsburgh Pirates 4
- Chicago Cubs 6 – Detriot Tigers 4 (See Chicago Sports Recap)
- Minnesota Twins 7 – Milwaukee Brewers 8 (10 innings)
- Seattle Mariners 4 – Chicago White Sox 5 (10 innings) (See Chicago Sports Recap)
- Kansas City Royals 4 – Oakland Athletics 0
- San Francisco Giants 8 – Philadelphia Phillies 6 (10 innings)
- Cincinnati Reds 9 – Los Angeles Angels 4 (Game 1 of DH)
- Miami Marlins 0 – San Diego Padres 4
- Colorado Rockies 5 – Tampa Bay Rays 6 (10 innings)
- Toronto Blue Jays 0 – Baltimore Orioles 7
- Washington Nationals 1 – New York Yankees 9
- Los Angeles Dodgers 3 – Cleveland Guardians 1 (Suspended)
- New York Mets 0 – Atlanta Braves 7
- Boston Red Sox 7 – Houston Astros 5
- Cincinnati Reds 7 – Los Angeles Angels 3 (Game 2 of DH)