Scores:
- San Francisco Giants 5 – Colorado Rockies 9 (Game 1 of DH)
- Boston Red Sox 3 – Toronto Blue Jays 4 (13 innings)
- San Diego Padres 5 – Oakland Athletics 2
- Atlanta Braves 5 – Miami Marlins 11
- Texas Rangers 1 – Cleveland Guardians 2
- New York Yankees 6 – Pittsburgh Pirates 3
- Tampa Bay Rays 0 – Baltimore Orioles 8
- Cincinnati Reds 3 – New York Mets 2
- Houston Astros 8 – Kansas City Royals 10
- Minnesota Twins 6 – Chicago White Sox 7 (See Chicago Sports Recap)
- Washington Nationals 5 – Milwaukee Brewers 9
- Philadelphia Phillies 6 – St. Louis Cardinals 1
- Chicago Cubs 6 – Arizona Diamondbacks 7 (13 innings) (See Chicago Sports Recap)
- San Francisco Giants 2 – Colorado Rockies 5 (Game 2 of DH)
- Detroit Tigers 5 – Los Angeles Angels 5 (10 innings)
- Los Angeles Dodgers 6 – Seattle Mariners 2 (11 innings)